contig_1_Soce448 - Region 1 - lanthipeptide-class-ii,proteusin
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
lanthipeptide-class-ii: cds(LANC_like and DUF4135) proteusin: (PoyD or TIGR03793)
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme. Includes CompaRiPPson results for any available databases, with a detailed explanation here.
Lanthipeptide(s) for ctg1_817
allorf_01106291_01106416
Leader:
MGEPQQPRTTRRGAARRRPSPGG
Core:
APGARQGSSCSRPAGRTR
Core with dehydrations:
APGARQGDhaDhaCysDhaRPAGRDhbR
antiSMASH-DB 4.0 matches for allorf_01106291_01106416
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.
allorf_01106291_01106416 - Class II
Cleavage pHMM score: -3.80
RODEO score: 0
Monoisotopic mass: 1741.9 Da
Molecular weight: 1742.9 Da
Number of bridges: 1
Alternative weights
(assuming N unmodified Ser/Thr residues)
1760.9 Da N = 1
1778.9 Da N = 2
1797.0 Da N = 3
allorf_01113483_01113587 - Class II
Cleavage pHMM score: -6.50
RODEO score: 0
Monoisotopic mass: 1540.8 Da
Molecular weight: 1541.7 Da
Number of bridges: 1
Alternative weights
(assuming N unmodified Ser/Thr residues)
1559.8 Da N = 1
1577.8 Da N = 2
1595.8 Da N = 3
1613.8 Da N = 4
allorf_01113986_01114174 - Class II
Cleavage pHMM score: -5.80
RODEO score: 0
Monoisotopic mass: 2202.2 Da
Molecular weight: 2203.5 Da
Number of bridges: 1
allorf_01114709_01114819 - Class II
Cleavage pHMM score: -4.00
RODEO score: 0
Monoisotopic mass: 2420.2 Da
Molecular weight: 2421.7 Da
Number of bridges: 1
Alternative weights
(assuming N unmodified Ser/Thr residues)
2439.7 Da N = 1
allorf_01114724_01114936 - Class II
Cleavage pHMM score: -6.50
RODEO score: 0
Monoisotopic mass: 1124.5 Da
Molecular weight: 1125.3 Da
Number of bridges: 1
Alternative weights
(assuming N unmodified Ser/Thr residues)
1143.3 Da N = 1
1161.3 Da N = 2
allorf_01116299_01116487 - Class II
Cleavage pHMM score: -1.00
RODEO score: 0
Monoisotopic mass: 5172.4 Da
Molecular weight: 5175.5 Da
Number of bridges: 2
Alternative weights
(assuming N unmodified Ser/Thr residues)
5193.5 Da N = 1
5211.5 Da N = 2
5229.5 Da N = 3
5247.6 Da N = 4
5265.6 Da N = 5
allorf_01106291_01106416 - Class II
Cleavage pHMM score: -3.80
RODEO score: 0
Monoisotopic mass: 1741.9 Da
Molecular weight: 1742.9 Da
Number of bridges: 1
Alternative weights
(assuming N unmodified Ser/Thr residues)
1760.9 Da N = 1
1778.9 Da N = 2
1797.0 Da N = 3
allorf_01106291_01106416 - Class II
Cleavage pHMM score: -3.80
RODEO score: 0
Monoisotopic mass: 1741.9 Da
Molecular weight: 1742.9 Da
Number of bridges: 1
Alternative weights
(assuming N unmodified Ser/Thr residues)
1760.9 Da N = 1
1778.9 Da N = 2
1797.0 Da N = 3
allorf_01113483_01113587 - Class II
Cleavage pHMM score: -6.50
RODEO score: 0
Monoisotopic mass: 1540.8 Da
Molecular weight: 1541.7 Da
Number of bridges: 1
Alternative weights
(assuming N unmodified Ser/Thr residues)
1559.8 Da N = 1
1577.8 Da N = 2
1595.8 Da N = 3
1613.8 Da N = 4
allorf_01113986_01114174 - Class II
Cleavage pHMM score: -5.80
RODEO score: 0
Monoisotopic mass: 2202.2 Da
Molecular weight: 2203.5 Da
Number of bridges: 1
allorf_01114709_01114819 - Class II
Cleavage pHMM score: -4.00
RODEO score: 0
Monoisotopic mass: 2420.2 Da
Molecular weight: 2421.7 Da
Number of bridges: 1
Alternative weights
(assuming N unmodified Ser/Thr residues)
2439.7 Da N = 1
allorf_01114724_01114936 - Class II
Cleavage pHMM score: -6.50
RODEO score: 0
Monoisotopic mass: 1124.5 Da
Molecular weight: 1125.3 Da
Number of bridges: 1
Alternative weights
(assuming N unmodified Ser/Thr residues)
1143.3 Da N = 1
1161.3 Da N = 2
allorf_01116299_01116487 - Class II
Cleavage pHMM score: -1.00
RODEO score: 0
Monoisotopic mass: 5172.4 Da
Molecular weight: 5175.5 Da
Number of bridges: 2
Alternative weights
(assuming N unmodified Ser/Thr residues)
5193.5 Da N = 1
5211.5 Da N = 2
5229.5 Da N = 3
5247.6 Da N = 4
5265.6 Da N = 5
contig_1_Soce448 - Region 2 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 3 - thioamitides
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 4 - PKS-like,T1PKS,T3PKS,transAT-PKS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
PKS-like: (t2pks2 or ksIII) T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT) T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 1540265 - 1630906:
Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ctg1_1153: pk
PKS_AT (10..302): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 54.2%
minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 24.9
Methylmalonyl-CoA: 14.6
Malonyl-CoA: 13.4
Isobutyryl-CoA: 13.2
inactive: 10.3
Benzoyl-CoA: 8.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0
ctg1_1154: mal
PKS_AT (4..278): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
inactive: 66.7%
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 84.0
inactive: 27.5
Methoxymalonyl-CoA: 19.5
Methylmalonyl-CoA: 16.3
Propionyl-CoA: 15.9
fatty_acid: 12.8
trans-1,2-CPDA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0
ctg1_1158: mmal
PKS_AT (562..853): mmal
ATSignature: Methylmalonyl-CoA
Top 3 matches:
Methylmalonyl-CoA: 79.2%
Malonyl-CoA: 75.0%
Methoxymalonyl-CoA: 70.8%
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 171.6
Ethylmalonyl-CoA: 151.3
Methoxymalonyl-CoA: 128.6
Malonyl-CoA: 105.2
2-Methylbutyryl-CoA: 87.3
Propionyl-CoA: 82.6
trans-1,2-CPDA: 72.4
Isobutyryl-CoA: 58.6
CHC-CoA: 57.8
Benzoyl-CoA: 48.6
Acetyl-CoA: 43.1
inactive: 42.9
fatty_acid: 26.3
3-Methylbutyryl-CoA: 14.7
contig_1_Soce448 - Region 5 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 11, location 2772959 - 2825493:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:
ala (Ala)
Stachelhaus prediction details:
Stachelhaus sequence:
DVMSCAGVLK
Nearest Stachelhaus code(s):
Ala DVGFVAGVLK (53% 8Å match)
Stachelhaus code match:
70% (weak)
contig_1_Soce448 - Region 6 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
NRPS/PKS substrates
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
contig_1_Soce448 - Region 7 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
NRPS/PKS substrates
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
contig_1_Soce448 - Region 8 - lanthipeptide-class-i
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03604))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme. Includes CompaRiPPson results for any available databases, with a detailed explanation here.
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.
ctg1_2608 - Class I
Cleavage pHMM score: -8.70
RODEO score: 20
Monoisotopic mass: 2399.0 Da
Molecular weight: 2400.8 Da
Number of bridges: 7
contig_1_Soce448 - Region 9 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 10 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 11 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 12 - hglE-KS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 18, location 5093917 - 5149483:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ctg1_3826: mal
PKS_AT (577..869): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
inactive: 62.5%
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 103.7
Methoxymalonyl-CoA: 59.4
Methylmalonyl-CoA: 47.1
inactive: 23.2
Propionyl-CoA: 22.0
Isobutyryl-CoA: 19.2
fatty_acid: 19.1
Ethylmalonyl-CoA: 12.3
trans-1,2-CPDA: 11.5
CHC-CoA: 7.3
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: -2.2
contig_1_Soce448 - Region 13 - LAP,thiopeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
LAP: ((((goadsporin_like or PF00881 or TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or TIGR03603 or TIGR03602) and not cyanobactin_synth) thiopeptide: ((YcaO or TIGR03604) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Thiopeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Thiopeptide predictions
Lists the possible core peptides for each biosynthetic enzyme. Predicted tail sequences are also shown, if present. Includes CompaRiPPson results for any available databases, with a detailed explanation here.
No core peptides found.
Thiopeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its possible molecular weights and the scores for cleavage site prediction and RODEO. If relevant, other features, such as macrocycle and amidation, will also be listed.
No core peptides found.
contig_1_Soce448 - Region 14 - phenazine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 15 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 16 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
NRPS: cds(Condensation and (AMP-binding or A-OX)) T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 22, location 5639587 - 5698975:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
DVENIGAITK
Nearest Stachelhaus code(s):
Arg DVENVGAITK (76% 8Å match)
Stachelhaus code match:
90% (moderate)
contig_1_Soce448 - Region 17 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 18 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
NRPS: cds(Condensation and (AMP-binding or A-OX)) T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 24, location 5852367 - 5903932:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:
Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:
leu (Leu)
Stachelhaus prediction details:
Stachelhaus sequence:
DAWFLGNVVK
Nearest Stachelhaus code(s):
Leu DAWFLGNVVK (94% 8Å match)
Stachelhaus code match:
100% (strong)
PKS_AT (3085..3375): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 66.7%
2-Rhyd-Malonyl-CoA: 54.2%
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 114.1
Methoxymalonyl-CoA: 65.0
Methylmalonyl-CoA: 50.9
inactive: 44.1
Propionyl-CoA: 29.0
Ethylmalonyl-CoA: 26.0
Acetyl-CoA: 16.2
Benzoyl-CoA: 13.8
2-Methylbutyryl-CoA: 13.8
fatty_acid: 12.9
Isobutyryl-CoA: 12.4
CHC-CoA: 9.5
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0
contig_1_Soce448 - Region 19 - LAP,thioamitides
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
thioamitides: ((YcaO or TIGR03604) and TfuA) LAP: ((((goadsporin_like or PF00881 or TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or TIGR03603 or TIGR03602) and not cyanobactin_synth)
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 20 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 21 - LAP,thioamitides,thiopeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
thioamitides: ((YcaO or TIGR03604) and TfuA) LAP: ((((goadsporin_like or PF00881 or TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or TIGR03603 or TIGR03602) and not cyanobactin_synth) thiopeptide: ((YcaO or TIGR03604) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Thiopeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Thiopeptide predictions
Lists the possible core peptides for each biosynthetic enzyme. Predicted tail sequences are also shown, if present. Includes CompaRiPPson results for any available databases, with a detailed explanation here.
No core peptides found.
Thiopeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its possible molecular weights and the scores for cleavage site prediction and RODEO. If relevant, other features, such as macrocycle and amidation, will also be listed.
No core peptides found.
contig_1_Soce448 - Region 22 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 23 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 29, location 7520871 - 7564903:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:
Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:
val (Val)
Stachelhaus prediction details:
Stachelhaus sequence:
DAFFVGGTFK
Nearest Stachelhaus code(s):
Val DAFFVGGTFK (82% 8Å match)
Stachelhaus code match:
100% (strong)
contig_1_Soce448 - Region 24 - NRP-metallophore,NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
NRP-metallophore: (VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL))) NRPS: cds(Condensation and (AMP-binding or A-OX)) T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 30, location 7920630 - 8003576:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:
asp,asn (Asp, Asn)
Single AA prediction:
asp (Asp)
Stachelhaus prediction details:
Stachelhaus sequence:
DLTKVGHVGK
Nearest Stachelhaus code(s):
Asp DLTKVGHVGK (85% 8Å match)
Stachelhaus code match:
100% (strong)
contig_1_Soce448 - Region 25 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 31, location 8185780 - 8295449:
Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ctg1_6108: mal - mal - mal
PKS_AT (570..860): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 95.8%
inactive: 87.5%
2-Rhyd-Malonyl-CoA: 54.2%
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 207.3
inactive: 125.6
Methoxymalonyl-CoA: 70.5
Methylmalonyl-CoA: 52.2
Isobutyryl-CoA: 31.9
Propionyl-CoA: 30.7
Benzoyl-CoA: 21.7
Acetyl-CoA: 16.2
2-Methylbutyryl-CoA: 15.1
trans-1,2-CPDA: 12.0
Ethylmalonyl-CoA: 8.9
CHC-CoA: 2.8
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0
PKS_AT (2346..2636): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 95.8%
inactive: 87.5%
2-Rhyd-Malonyl-CoA: 54.2%
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 207.3
inactive: 125.6
Methoxymalonyl-CoA: 70.5
Methylmalonyl-CoA: 52.2
Isobutyryl-CoA: 31.9
Propionyl-CoA: 30.7
Benzoyl-CoA: 21.7
Acetyl-CoA: 16.2
2-Methylbutyryl-CoA: 15.1
trans-1,2-CPDA: 12.0
Ethylmalonyl-CoA: 8.9
CHC-CoA: 2.8
fatty_acid: 0.0
3-Methylbutyryl-CoA: 0.0
PKS_AT (4115..4412): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 95.8%
inactive: 83.3%
2-Rhyd-Malonyl-CoA: 58.3%
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 222.9
inactive: 137.3
Methoxymalonyl-CoA: 75.1
Methylmalonyl-CoA: 64.5
Propionyl-CoA: 36.9
Isobutyryl-CoA: 36.9
2-Methylbutyryl-CoA: 24.6
Ethylmalonyl-CoA: 22.9
Acetyl-CoA: 21.4
Benzoyl-CoA: 20.0
CHC-CoA: 13.7
fatty_acid: 8.9
trans-1,2-CPDA: 2.4
3-Methylbutyryl-CoA: 0.0
ctg1_6109: mal
PKS_AT (568..868): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 100.0%
inactive: 83.3%
2-Rhyd-Malonyl-CoA: 54.2%
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 212.5
inactive: 127.0
Methoxymalonyl-CoA: 54.4
Methylmalonyl-CoA: 40.7
Propionyl-CoA: 23.4
Acetyl-CoA: 22.3
Benzoyl-CoA: 17.8
Isobutyryl-CoA: 14.7
fatty_acid: 9.8
2-Methylbutyryl-CoA: 9.8
Ethylmalonyl-CoA: 6.6
trans-1,2-CPDA: 0.0
CHC-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
ctg1_6110: mmal - mal - mal
PKS_AT (570..868): mmal
ATSignature: Methylmalonyl-CoA
Top 3 matches:
Methylmalonyl-CoA: 100.0%
Methoxymalonyl-CoA: 95.8%
Ethylmalonyl-CoA: 91.7%
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 208.7
Ethylmalonyl-CoA: 199.6
Methoxymalonyl-CoA: 174.5
2-Methylbutyryl-CoA: 151.2
trans-1,2-CPDA: 135.8
Propionyl-CoA: 120.9
CHC-CoA: 104.7
Isobutyryl-CoA: 96.8
Malonyl-CoA: 89.0
Benzoyl-CoA: 79.8
Acetyl-CoA: 59.6
fatty_acid: 48.2
3-Methylbutyryl-CoA: 48.0
inactive: 31.0
PKS_AT (2122..2422): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 95.8%
inactive: 83.3%
2-Rhyd-Malonyl-CoA: 54.2%
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 224.9
inactive: 135.1
Methoxymalonyl-CoA: 64.1
Methylmalonyl-CoA: 47.8
Propionyl-CoA: 33.7
Isobutyryl-CoA: 24.9
Acetyl-CoA: 20.8
Benzoyl-CoA: 17.0
2-Methylbutyryl-CoA: 15.0
Ethylmalonyl-CoA: 6.3
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
CHC-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
PKS_AT (3680..3980): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 95.8%
inactive: 83.3%
2-Rhyd-Malonyl-CoA: 54.2%
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 224.9
inactive: 135.1
Methoxymalonyl-CoA: 64.1
Methylmalonyl-CoA: 47.8
Propionyl-CoA: 33.7
Isobutyryl-CoA: 24.9
Acetyl-CoA: 20.8
Benzoyl-CoA: 17.0
2-Methylbutyryl-CoA: 15.0
Ethylmalonyl-CoA: 6.3
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
CHC-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
ctg1_6111: mmal
PKS_AT (562..857): mmal
ATSignature: Methylmalonyl-CoA
Top 3 matches:
Methylmalonyl-CoA: 100.0%
Methoxymalonyl-CoA: 95.8%
Ethylmalonyl-CoA: 91.7%
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 213.3
Ethylmalonyl-CoA: 208.9
Methoxymalonyl-CoA: 182.0
2-Methylbutyryl-CoA: 147.2
trans-1,2-CPDA: 142.0
Propionyl-CoA: 117.8
CHC-CoA: 103.9
Isobutyryl-CoA: 101.9
Malonyl-CoA: 101.6
Benzoyl-CoA: 78.8
Acetyl-CoA: 65.3
fatty_acid: 53.2
3-Methylbutyryl-CoA: 45.9
inactive: 35.7
ctg1_6112: pk - pk
PKS_AT (567..865): pk
ATSignature: Ethylmalonyl-CoA
Top 3 matches:
Ethylmalonyl-CoA: 83.3%
Methylmalonyl-CoA: 79.2%
Methoxymalonyl-CoA: 79.2%
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 168.2
Ethylmalonyl-CoA: 160.1
Methoxymalonyl-CoA: 145.6
2-Methylbutyryl-CoA: 116.4
trans-1,2-CPDA: 104.8
Propionyl-CoA: 86.9
CHC-CoA: 73.5
Isobutyryl-CoA: 69.6
Malonyl-CoA: 63.1
Benzoyl-CoA: 55.3
3-Methylbutyryl-CoA: 46.9
Acetyl-CoA: 42.0
fatty_acid: 25.4
inactive: 19.9
PKS_AT (2124..2420): pk
ATSignature: Methylmalonyl-CoA
Top 3 matches:
Methylmalonyl-CoA: 100.0%
Malonyl-CoA: 91.7%
Methoxymalonyl-CoA: 91.7%
minowa: Ethylmalonyl-CoA
Prediction, score:
Ethylmalonyl-CoA: 222.5
Methylmalonyl-CoA: 220.4
Methoxymalonyl-CoA: 187.6
2-Methylbutyryl-CoA: 151.4
trans-1,2-CPDA: 134.5
Propionyl-CoA: 117.9
CHC-CoA: 115.0
Malonyl-CoA: 104.8
Isobutyryl-CoA: 98.7
Benzoyl-CoA: 84.9
Acetyl-CoA: 61.2
fatty_acid: 49.4
3-Methylbutyryl-CoA: 41.0
inactive: 37.2
ctg1_6113: mmal - mal
PKS_AT (568..864): mmal
ATSignature: Methylmalonyl-CoA
Top 3 matches:
Methylmalonyl-CoA: 100.0%
Methoxymalonyl-CoA: 95.8%
Ethylmalonyl-CoA: 91.7%
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 213.1
Ethylmalonyl-CoA: 210.2
Methoxymalonyl-CoA: 171.7
2-Methylbutyryl-CoA: 139.6
trans-1,2-CPDA: 134.5
Propionyl-CoA: 110.9
Malonyl-CoA: 106.1
CHC-CoA: 100.7
Isobutyryl-CoA: 87.7
Benzoyl-CoA: 84.4
Acetyl-CoA: 72.5
inactive: 47.4
3-Methylbutyryl-CoA: 41.5
fatty_acid: 40.9
PKS_AT (2118..2418): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 95.8%
inactive: 83.3%
2-Rhyd-Malonyl-CoA: 54.2%
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 224.9
inactive: 135.1
Methoxymalonyl-CoA: 64.1
Methylmalonyl-CoA: 47.8
Propionyl-CoA: 33.7
Isobutyryl-CoA: 24.9
Acetyl-CoA: 20.8
Benzoyl-CoA: 17.0
2-Methylbutyryl-CoA: 15.0
Ethylmalonyl-CoA: 6.3
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
CHC-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
ctg1_6114: pk - mal
PKS_AT (617..913): pk
ATSignature: Benzoyl-CoA
Top 3 matches:
Benzoyl-CoA: 95.8%
Methylmalonyl-CoA: 66.7%
Malonyl-CoA: 62.5%
minowa: Benzoyl-CoA
Prediction, score:
Benzoyl-CoA: 172.5
Methylmalonyl-CoA: 115.1
Isobutyryl-CoA: 103.5
Methoxymalonyl-CoA: 92.3
Ethylmalonyl-CoA: 89.3
Malonyl-CoA: 58.5
trans-1,2-CPDA: 53.7
Acetyl-CoA: 52.9
3-Methylbutyryl-CoA: 51.2
2-Methylbutyryl-CoA: 50.0
Propionyl-CoA: 44.2
CHC-CoA: 43.6
inactive: 24.3
fatty_acid: 24.0
PKS_AT (1037..1338): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 95.8%
inactive: 83.3%
2-Rhyd-Malonyl-CoA: 54.2%
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 198.2
inactive: 110.5
Methoxymalonyl-CoA: 62.7
Methylmalonyl-CoA: 51.6
Isobutyryl-CoA: 32.8
Benzoyl-CoA: 26.6
Propionyl-CoA: 21.8
Acetyl-CoA: 21.3
Ethylmalonyl-CoA: 11.2
fatty_acid: 9.7
trans-1,2-CPDA: 6.4
CHC-CoA: 3.0
2-Methylbutyryl-CoA: 2.5
3-Methylbutyryl-CoA: 0.0
contig_1_Soce448 - Region 26 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
NRPS/PKS substrates
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ctg1_6227: X
AMP-binding (611..1034): X
nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 28 - NRP-metallophore,NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
NRP-metallophore: (VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL))) NRPS: cds(Condensation and (AMP-binding or A-OX))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 34, location 9170356 - 9224162:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
phosphonate: (phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 30 - microviridin
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 31 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 32 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
NRPS: cds(Condensation and (AMP-binding or A-OX)) T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 38, location 9866304 - 9928647:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
NRPS: cds(Condensation and (AMP-binding or A-OX)) T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 39, location 10167873 - 10218916:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:
Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:
leu (Leu)
Stachelhaus prediction details:
Stachelhaus sequence:
DAWFLGNVVK
Nearest Stachelhaus code(s):
Leu DAWFLGNVVK (97% 8Å match)
Stachelhaus code match:
100% (strong)
PKS_AT (3097..3294): mal
ATSignature: (unknown)
No matches above 50%
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 24.0
Methylmalonyl-CoA: 18.8
Methoxymalonyl-CoA: 16.0
fatty_acid: 9.0
inactive: 8.6
trans-1,2-CPDA: 7.5
Propionyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0
contig_1_Soce448 - Region 34 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) NRPS: cds(Condensation and (AMP-binding or A-OX))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 40, location 10373214 - 10423913:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:
Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:
val (Val)
Stachelhaus prediction details:
Stachelhaus sequence:
DTFWVGGTFK
Nearest Stachelhaus code(s):
Ala DTFWLGGTFK (74% 8Å match)
Val DAFWVGGTFK (59% 8Å match)
Stachelhaus code match:
90% (moderate)
contig_1_Soce448 - Region 35 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 36 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 37 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 38 - LAP,RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) LAP: ((((goadsporin_like or PF00881 or TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or TIGR03603 or TIGR03602) and not cyanobactin_synth)
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 39 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
NRPS/PKS substrates
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
contig_1_Soce448 - Region 40 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 41 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
No matches found.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
contig_1_Soce448 - Region 42 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key. More detailed help is available here.
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
Legend:
core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region. Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection. Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features
Identifier
Product
Length
Function
Sequence
NCBI Blast
Filter details
NT
AA
NT
AA
No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details. A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar gene clusters
Shows regions from the antiSMASH database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region. Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship. Click on reference genes to show details of similarities to genes within the current region.
No matches found.
NRPS/PKS substrates
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
reset view
zoom to selection