LOCUS       contig_1_Soce448       13455 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  contig_1_Soce448.
ACCESSION   contig_1_Soce448
VERSION     contig_1_Soce448
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-19 23:46:11
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 9444377
            Orig. end    :: 9457832
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13455
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8455]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8455
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..13455
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13455
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="29"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(1288..2538)
                     /locus_tag="ctg1_7039"
                     /transl_table=11
                     /translation="MRRYQFTSESVTEGHPDKVCDQISDAILDGILEKDPTARVACETL
                     VKTGMAVVAGEITTSAWVDMPVVVRNTIKDIGYTDAAMGFDYETCAVLTAIEKQSPDIS
                     RGVTEGEGLFKEQGAGDQGLMFGYATDETSELMPSPISYAHRLARKLADLRKSKKLDWL
                     RPDGKTQVTIEYEDQTPVRVSAVVVSTQHSPEVKHKTIVDAVRSLIIEKSIPAKLMDRN
                     TKIYVNPTGRFVVGGPYGDAGLTGRKIIVDTYGGMGRHGGGAFSGKDPTKVDRSACYYA
                     RYVAKNVVASKLAARCEVQIAYAIGVAQPVGVHVNTFGTGRVGEDVLEKYIMQNFDMRP
                     KAIIEQLDLLKPIYRKTAAYGHFGRDEFTWEKTDRAAKLAEDLLRPTLAAVPAATNGSG
                     SKKEPKRKGKKEVGAQA"
     CDS             2793..3197
                     /locus_tag="ctg1_7040"
                     /transl_table=11
                     /translation="MPRMTFDEIKACLEREGWAVEVVSNDTLRSDFQGAERLFPLFVRL
                     APPFVVFAVIPFVRLPMELEEGDAIVRRLLQLNREINMAKLSADEEGDVILSVEYRLED
                     LDPSEVRDAVDVLSFYANKHYAELVALAAQ"
     CDS             complement(3216..3584)
                     /locus_tag="ctg1_7041"
                     /transl_table=11
                     /translation="MANRSWSAALLLVAAGCTASVGSIGAVLGRDNESLALYVRDVPPG
                     LAAERAGLIPGDEIMMIDGVYVRDLPSAAVRDRLRGAVGSAVELTVVRGRDVRRVRIVR
                     TELRAHEGLKPREEQILP"
     CDS             3998..4951
                     /locus_tag="ctg1_7042"
                     /transl_table=11
                     /translation="MPEPRAAAESSTPAAQSGGVPGGWKMRMEDPLNRYYRYPIARWIV
                     RGLMRTPVTPNQVTLVQPLFAALAGYLVTFDDPGHLIAGALVFELRSILDCVDGALARA
                     KRMVSPAGHAIDGLADWLGVVFLYAGIFWHLHLHPPPEGPWSATVSTNALLLIALLQGA
                     LRSFSADYFKLKYCSIFETGTDETADVLRRKIQALGPSSSFFAHFDVFIGRMGHLAFEH
                     EWFDPRRSRSSTSADQVKQLIREEASPLTRLIGALWAISNGDAFLSMVVLTLLVNQLWL
                     GQVFFATGGVVWIVAVIGLNGWFLRGASRRAKLAVA"
     CDS             complement(5001..5708)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_7043"
                     /sec_met_domain="NTP_transf_3 (E-value: 2e-18, bitscore:
                     66.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAILLAAGRGRRIGRDAPKCLISIEGKTLLERHLVNLTESGVTD
                     LTIVVGFRHEMIEEALASLRPSLKIELVKNPRFTHGSIVSLHVAADRLSGGGLWMDADV
                     LYPAALLRRLVSSPHENCLLVDASSEESGEEMMVGVRAGRVLKIARRVGKDWDLAGETV
                     GFAKVGPQGGRTMQRLLEEEVSAGRLDQEYEAAMDRAFQEVPFGIERVDDLPWTEIDFE
                     EDVEKARRLAAAL"
     CDS             complement(5705..6268)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_7044"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-17, bitscore:
                     62.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLEALKVFTAAVGKDDLVVCCNGMIGRELYTTQDRPSNFYMIG
                     SMGLGLSIGLGLSLAQPRKRIFVLDGDGNVLMGMNALASVGSERPANLVHVVLDNRSHA
                     STGGQRTISGDVKLESVASAVGYRATHRADSVESFEASLRVALVQPGPVMVLALVDGGT
                     VKGIGRVAETPQELAARFAAEARR"
     CDS             complement(6265..6786)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_7045"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.5e-10, bitscore:
                     39.4, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHGSHGSGKSYAPEFVAALKEAGFDFFAGVPCSLLKGLVSLLDA
                     DASARYISATREDSAIGMAFGAWLGGRLPMVLMQNSGLGVSVNALASLSTMYEVPALLV
                     ISWRGEGGNDAPEHIMMGEIMLPILDLMKIQHRVLRAAEPMGPQVQWAKDVMLSTRQPA
                     ALIVPAGVLE"
     CDS             complement(6791..8455)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonates-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 271.8;
                     E-value: 1.1e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_7046"
                     /note="smCOG tree PNG image: smcogs/ctg1_7046.png"
                     /sec_met_domain="phosphonates-like (E-value: 3.3e-134,
                     bitscore: 445.4, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.5e-98, bitscore:
                     328.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.2e-67, bitscore:
                     226.3, seeds: 69, tool: rule-based-clusters)"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.6e-13, bitscore:
                     49.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKARKLRELMARPGPIVIIGAHNGLSAKIGEEAGFDGLWASGFE
                     ISASYAVPDANILTMAENLQAAKMMNSTSLPVVADCDNGYGNAVNVVRCVEEYEAAGIA
                     AICMEDNIFPKRCSFYAGVKRELADVEEHALKVRAAKATQKDRDFVVIARTEALIAGWG
                     MEEALRRGRAYADAGADMVLIHSKSKDPDEVLSFARAWDRPNTPLVCVPTIYRTTSVDT
                     LHKAGFKLIIFANHAIRSSIKAMTETLQTLKREMYTGSVDDKVVPLERVYQLVGVDKMK
                     QEESSFLPSGSPGVTAVILAAGQSQGLLPLTEELPKPMLDLKGKSILERQIDVLNACGV
                     KDVAVVRGYKKEAIKVPNVRFYDNDEYATTNEVSSLFRASKELSGPFLFLYGDIVFERG
                     HLEKLLKSPADISIVVDRAYAEGQRPKDARGVPDLVALKDAQEAGYRFVGAEAPHRVAR
                     VGRAIPAGEAHGEFVGMAMFTAKGARLLTDCYHQLQETRAKGGFHEAESLRNASFTDLL
                     QELIDRGADVQAIDVYKGWLEIDTFEDYRRAWALIKE"
     CDS             complement(8790..9101)
                     /locus_tag="ctg1_7047"
                     /transl_table=11
                     /translation="MPTVVFEDGALGPAVTAEAGAGRLIDVCDDARAPIVFSCRDARCA
                     TCRVEVVEGEQLLEPPARGERDLLDRLGAPPRLRLACQAVLRAGPGLVRLRGVVGREG"
     CDS             9182..10471
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 316.2; E-value: 6.9e-96)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_7048"
                     /note="smCOG tree PNG image: smcogs/ctg1_7048.png"
                     /sec_met_domain="Trp_halogenase (E-value: 3.5e-18,
                     bitscore: 64.9, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDRWDAIILGGGPGGSTLAASLARLGRRALVLERERFPRFHIGE
                     SLLPLSREVFERLGLDEELDARFLRKYGARFLCSSTGRTRTYSFADAFEPRFEFAYQVQ
                     RDAFDQLLLRHAAELGAEVRESWEAVEVMFEGPRAVGVRARPRARPDGAGPEEAAAARA
                     DSSDVVELRAPVIVDATGRDTLLASRMRRKAQLAELDKTALFTHYEGVPREAGIHQGDI
                     QIVLFEHGWFWFIPFRGEVTSVGAVVSSSWIRGRAKGERLDELFDRTVAQSGWAREFLA
                     SARRIRPVGALADFSYRIDQLAGDGWLFVGDAGGFLDPLFSTGAHLAIKGADLAATAIH
                     RALDAGDTSRAAFSAYEAEIRYAVDLFLGVVQGFYKGQFRETLFEPNQRPTMRKLITSM
                     LAGDVFHAERRPQWASFLRQQYPAEVPAFA"
     CDS             complement(10541..10882)
                     /locus_tag="ctg1_7049"
                     /transl_table=11
                     /translation="MARAHLALLLWGTFALGCGKAGGDPGKADLDSTGVDACDSYLATM
                     TTCASKLPAESRKSHEAAIRIARDVLEARAEADDEALKGDARAEARVALAAACKQMSDA
                     VLDREACGP"
     CDS             complement(11055..12353)
                     /locus_tag="ctg1_7050"
                     /transl_table=11
                     /translation="MSTPRSADPKPKPGPQQKAHAGRPASQERRALTHIGGATVLEGDP
                     ESAAKLAHALDVASSSTAEEAARAHVHGFHSYPARMHPDTARRLIEGLSRPGERVLDPF
                     CGSGTVLVEARLSGRAAIGVDANPLAVRLARLKVQGSTPGERERLVAAAREVAAAADER
                     RKARAGPSRRYGPEDVALFEPHVLLELDGLRVGLDRLAGHGADALRADLELVLSAILTK
                     LSRRTSDTSEHELPRRIAAGYPARLFIRKAEELAQRLAEVAVPLAASPPALVEEGDARV
                     LRGVEAGSVHLAITSPPYPGVYDYLAHHEARLRWLRLRSARFEQDEIGARRHLDPLGPE
                     AGRARWRDELGGVLTALARVLRSGAPLVLLIADSVVAGAPVYAVDVVRAAASGARFAVR
                     AVASQPRPHFHRPTARAFQRRPRHEHAILLIRA"
     CDS             complement(12331..13137)
                     /locus_tag="ctg1_7051"
                     /transl_table=11
                     /translation="MSDASPGAARCRVCDAALAPEGDRCPQCGAAARAEACPHCGGVTG
                     ASAHLELRFACDACGGPRVPVADARVERSGREVPLLQKARAAASARSVWRAAGVAASAL
                     LGFELFLFAVLLLVLGASVGLFTAGLLTMAPVGAFALWALRRAKSRSRDIAPALDAAWV
                     SVASDVARQAEGPLTAGGLASTLRIAESQAEELLALLEVNDVVRGAIGPAGEFGYAPKL
                     RVGAARDEDRGEAGAESVAHALAAEEEAFAAEPLTQRTAHVDPAKR"
ORIGIN
        1 tggccatcga tgaggttggc cggccgcggt gagaggaacg cgacgaagta gtcgttgaag
       61 ctgtcgcaga cgacgggcca gtcgaacgtg acgtaattga cgttgaacgc gaagccgcgg
      121 acgttcgacg ggacccggag ggtgatctcg acggcggtcg ggtcggacgg cttcgcgagc
      181 accagatcgt cacagccgcg ggggtccttc gggaagtctt cggggaaatc accttcgtat
      241 ttcttgtcga agccttgcgg gctctcgaac ccctcgtcgt tctgcgtccg cgccgtgccg
      301 ctcgagaggg cgagcagccg cgtgcccgcc ctcggcggga cgttgggccc gaacttgggg
      361 aggatgccgt gcccgagatg gaagttggcg agcagctcgg cctcctgcgg cggcggcgcg
      421 ccgtcgacca tgacccaggc ggcggagacc acgccccagt cgtcgggccc ggacgacatc
      481 ttgcacagct cgaccgccct cgcggcgttg agcggatcca ggtcgtcgat cgggatcccg
      541 tcgtcgcacg gctcgggcac gttgtcgggg atgccgtcgc agtcgtcgtc cacgggctcc
      601 ggcgaggctc ccccttctcc agcgatcgtc gggagctcga gcgctcgcgg gttgatcagc
      661 gcgttgcaat cgtcgcagtc gccgtcgagc tccgtgaagc cgtcgccgtc gtcgtcggcg
      721 tccggcgagc cgctgcagcc cgcgcccccc gcacccacgc ccgcggacgt ggcgacggtc
      781 gtcgcgtcgg ccgtcgtttc ggctgtcgtg gtcggtgtcc cgccggtgct ggaggtgctg
      841 gaggcgctcg ccgcgccgcc ctctccgaca tcaaggccgc ctaccggtcc gatgttcccg
      901 gtgcaggccg tgcccagaca cccggccgca gtgatgaagc tcaagaaatt caaccaaggt
      961 ttcatcggtg ctcctcgagg tcgcatggaa ccagggaggt tcggtcgatc cggcgatacg
     1021 ggagtcgtcg atgattttat cagcagaagc ggccgcagca gtcagcccat cccggcaaat
     1081 gccggtgctt ttttgtgagg tgaatgccca catcatggcc cccgcatccg acccaggcgc
     1141 catggtcacg agcgctccag gagacgcggg tcgtggcgac aaaacgcaga gcgccggcgc
     1201 tttcacagcg ccggcgctct cggcctctcc gaggggccgt ccacggttcg ccccgctcac
     1261 ccgtagcggg cggagcgctc tgaacgatca ggcctgggcg cccacttcct tcttgccctt
     1321 gcgcttcggc tccttcttgc tcccggagcc gttcgtggcc gcggggaccg cggcgagcgt
     1381 cgggcgcagc aggtcctcgg ccagcttggc cgcgcggtcc gtcttctccc aggtgaactc
     1441 gtcacgcccg aagtggccgt acgcggccgt ctttcggtag atgggcttca gcaggtcgag
     1501 ctgctcgatg atcgccttcg gccgcatgtc gaagttctgc atgatgtact tctcgagcac
     1561 gtcctcacct acgcggcccg tgccgaaggt gttcacgtgg acgccgaccg gctgggcgac
     1621 gccgatggcg taggcgatct gcacctcgca gcgcgccgcg agcttggacg cgacgacgtt
     1681 cttcgcgacg tagcgcgcgt agtagcaggc ggagcgatcg accttcgtcg ggtccttgcc
     1741 gctgaaggcg ccgccgccgt gccggcccat gccgccgtag gtgtcgacga tgatcttgcg
     1801 gccggtgagg ccggcgtcgc cgtaggggcc gccgaccacg aagcggccgg tggggttcac
     1861 gtagatcttc gtgttccgat ccatcagctt ggccgggatg ctcttctcga tgatcaggct
     1921 ccgcaccgcg tcgacgatcg tcttgtgctt gacctcgggg ctgtgctgcg tcgacacgac
     1981 gacggcgctc acgcgcacgg gcgtctggtc ttcgtactcg atcgtgacct gggtcttgcc
     2041 gtcggggcgc agccagtcga gcttcttgga tttgcggaga tcggcgagct tccgggcgag
     2101 gcggtgggca tagctgatgg gggagggcat cagctccgac gtctcgtcgg tcgcataacc
     2161 gaacatgagc ccctggtcgc ctgccccctg ctccttgaag aggccctcgc cctcggtgac
     2221 gccgcgggag atgtcgggcg actgcttctc gatcgccgtg agcaccgcgc acgtctcgta
     2281 gtcgaagccc atcgcggcgt cggtgtagcc gatgtccttg atggtgttgc gcacgacgac
     2341 cggcatgtcg acccacgccg aggtggtgat ctcgccggcc acgacggcca tccccgtctt
     2401 caccagggtc tcgcacgcga cgcgggccgt cggatccttc tcgaggatcc cgtcgagaat
     2461 ggcgtcggag atctggtcgc acaccttgtc ggggtgtcct tcggtgacgg actcggatgt
     2521 gaactggtaa cggcgcatga atcgctcctt cggcggactc gaaatctgac ctctacgcat
     2581 agttcgagcg cggggcaccg tcaacgcgag ccgcggcctt ccacggacaa aagcgccggc
     2641 cggacgagct gcctccgggc tgtcggtgtg gacgtgaggg gtggacgcga ggtgggcgcg
     2701 agaccggacg agcggggggc gtcgggccgt cgatcggtcg cgctctcggc cggcgcgctc
     2761 gccccgagtg cgccgcgccg tcagaggcta tgatgccgcg catgacgttc gacgagatca
     2821 aggcgtgcct cgagcgcgag ggctgggctg tggaggtcgt atccaacgac accctgcgca
     2881 gcgacttcca gggggccgag cggctcttcc cgctgttcgt gcggctcgcg ccccccttcg
     2941 tcgtcttcgc ggtgatcccg ttcgtgcggc tgccgatgga gctcgaagag ggcgacgcga
     3001 tcgtgcggcg cctgctccag ctgaaccgcg agatcaacat ggccaagctc tcggccgacg
     3061 aggagggcga cgtgattctc agcgtcgagt accgcctcga ggacctcgat ccgagcgagg
     3121 tgcgcgacgc cgtcgatgtg ctctccttct acgcgaacaa gcactatgcc gagctcgtgg
     3181 cgctcgccgc gcaatgagcg gtcaccggcc ccgcttcaag gcaggatctg ctcctctctg
     3241 ggcttgagcc cctcgtgcgc ccttagctcg gtgcgcacga tccggacgcg ccgcacgtcg
     3301 cgcccgcgga cgacggtgag ctcgacggcg ctcccgacgg cgccgcggag ccgatcgcgc
     3361 accgctgccg acgggagatc ccggacatac acgccatcaa tcatcatgat ctcgtcgccc
     3421 gggatcagcc ccgctcgctc ggcggcgagg cccggcggca cgtcgcgcac gtagagcgcc
     3481 agcgactcgt tatctcgccc aaggacagcc ccgatggatc ccacgctcgc ggtgcacccc
     3541 gcggccacga gcaggagcgc cgcgctccag gacctgtttg ccaccgcggc accatagcgc
     3601 cgaggagccc cggcgcgccg ccattctcgc agggcgcccc ccgaagcgcg cggcggggcg
     3661 cggccgccac gtcagaccgg ctccagcgga cgcgcgcgct cgtcaaacgt cgcaacgtca
     3721 ctgcgccgca ggcgagagaa tgtgatttta caggaaggga gcgcccgagt gtgcctgtcg
     3781 cgtccgcacg cgaggtgcga agcgcggttc tcggtggggc ttcaggagcg caaacaacta
     3841 cgcggttggt cgccggaggt acgggatacg ccctggaaag tgcggcgtgg cgccgggacg
     3901 cgggcttgca gcgagctgtc acgccatgtc catcgagagg tcgcaatcca gttggtcccc
     3961 gggggcggct gtcctagagt ccaggccggg atcgccgatg cctgaaccgc gcgctgctgc
     4021 cgagagctcg acacctgccg cccagtccgg cggtgtgccc ggcggctgga agatgcggat
     4081 ggaggacccg ctcaatcgct actatcggta cccgatcgcg cgctggatcg tgcgggggct
     4141 gatgaggacg ccggtcacgc cgaaccaggt gacgctggtt cagccgctct tcgccgcgct
     4201 ggccggttac ctggtgacgt tcgatgatcc ggggcacctc atcgccgggg cgctcgtgtt
     4261 cgagctccgc tccatcctgg actgcgtgga cggcgcgctg gcgcgggcga agaggatggt
     4321 gagccccgcc ggtcacgcca ttgacggcct ggccgactgg ctgggcgtcg tcttccttta
     4381 tgccggcatc ttctggcacc ttcaccttca cccgccgccg gagggcccgt ggagcgcgac
     4441 cgtgtccacg aacgcactcc tgctgatcgc gctgctccag ggggcgctgc gctctttctc
     4501 cgcggactac ttcaagctca agtactgctc gatcttcgag acgggcaccg acgagacggc
     4561 ggacgtgctg cgccggaaga tccaggcgct cggcccctcc tcctcgttct ttgcccattt
     4621 cgatgtcttc atcgggcgca tggggcacct cgcgttcgag cacgagtggt tcgacccgcg
     4681 gcggagccgg tcctcgacca gcgcggatca ggtaaagcag ctgatccggg aggaggcgtc
     4741 gccgctcacg cgcctcatcg gcgcgctctg ggcgatatcg aacggcgacg cgttcctgtc
     4801 gatggtggtg ctgacgctcc tcgtgaacca gctctggctg ggtcaggtct tcttcgcgac
     4861 gggcggggtc gtctggatcg tcgcggtcat cgggctgaac ggctggttcc tccgcggcgc
     4921 atcccgtcgc gcgaagctgg ccgtggcctg agctcggcgc cctgcgccgc cgagctcagc
     4981 agtccccctc agcgcccgct ctagagagcg gctgccaggc ggcgggcctt ctccacgtct
     5041 tcttcgaagt cgatctcggt ccagggcagg tcgtcgacgc gctcgattcc gaacggcacc
     5101 tcctggaaag cgcggtccat cgcggcctcg tactcctggt cgaggcggcc ggcggagacc
     5161 tcctcctcca ggaggcgctg catcgtgcga ccgccctgcg ggccgacctt ggcgaagccg
     5221 acggtctcac cggcaaggtc ccagtccttg cccacgcggc gcgcgatctt gaggacgcgg
     5281 ccggcgcgga cgccgaccat catctcttcg ccgctctcct ccgagctcgc gtcgacaagc
     5341 aggcagttct cgtggggcga gctcacgagg cgccgcagca gcgcggcggg gtacagcacg
     5401 tcggcgtcca tccacagccc gccgcctgac agccggtcgg ccgccacgtg gagcgagacg
     5461 atgctgccgt gggtgaaccg cgggttcttg acgagctcga tcttcagcga agggcggagc
     5521 gaggcgagcg cctcctcgat catctcgtgc cggaagccga cgacgatcgt cagatcggtg
     5581 acgccgctct cggtgaggtt cacgaggtgg cgctcgagca gcgtcttgcc ctcgatcgag
     5641 atgaggcact tgggcgcgtc ccggccgatg cgccggccgc ggccggcggc gagcaggatc
     5701 gccctcatcg gcgcgcctcg gccgcgaagc gggcggcgag ctcctgcggc gtctccgcga
     5761 cgcggccgat gcccttcacg gtgccgccgt cgacgagggc gaggaccatg accgggcccg
     5821 gctgcacgag cgcgacgcgc agcgacgcct cgaaggactc gacggagtcg gcgcggtgcg
     5881 tggcgcggta gccgaccgcg ctggccaccg actcgagctt cacgtcgccc gagatcgtcc
     5941 gctgcccgcc ggtcgaagcg tgggagcggt tgtcgaggac gacgtgcacg aggttcgccg
     6001 gccgctcgct gccgacgctg gcgagcgcgt tcatgcccat gaggacgttg ccgtcgccgt
     6061 cgagcacgaa gatccgcttg cgcggctgcg cgagcgagag ccccaggccg atcgacaggc
     6121 cgagccccat cgagccgatc atgtagaagt tcgagggccg gtcctgcgtc gtgtagagct
     6181 cgcggccgat catgccgttg cagcagacca cgaggtcgtc cttgccgacc gccgccgtga
     6241 agaccttcag cgcttcgagc ttgttcattc gagcaccccc gcgggcacga tgagcgccgc
     6301 cggttgcctg gtggagagca tgacgtcctt cgcccactgc acctggggcc ccatcggctc
     6361 ggcggcgcgg aggacgcggt gctggatctt catcagatcg aggatgggga gcatgatctc
     6421 gcccatcatg atgtgctccg gggcgtcgtt gccgccctcg ccgcgccagg agatgacgag
     6481 cagcgcgggc acctcgtaca tcgtgctgag cgacgccagc gcgttcacgg agacgccgag
     6541 cccggagttc tgcatcagga ccatcggcag cctgccgccg agccaggcgc cgaacgccat
     6601 cccgatggcg ctgtcctcgc gggtcgcgga gatgtaacgg gcgctcgcgt cggcgtcgag
     6661 cagcgagaca aggcccttca acagcgagca gggcacgccc gcgaagaagt cgaaccccgc
     6721 ctccttgagc gcggcgacga actcgggcgc gtacgatttg cctgaaccgt gggaaccgtg
     6781 ggacatcgcc tcactccttg atgagcgccc aggcgcgacg gtagtcctcg aacgtgtcga
     6841 tctcgagcca ccccttgtaa acgtcgatcg cctgcacgtc cgcgccgcgg tcgatgagct
     6901 cctggagcag gtcggtgaag ctcgcgttgc ggagcgactc ggcctcgtgg aagccgccct
     6961 tcgcgcgggt ctcctgcagc tggtggtagc agtcggtgag caggcgcgcg cccttcgcgg
     7021 tgaacatggc catgcccacg aactcgccgt gcgcctcgcc cgcggggatc gcgcggccga
     7081 cgcgggccac ccggtgcggc gcctcggcgc cgacgaagcg gtagccggcc tcctgcgcgt
     7141 ccttcagggc cacgaggtcg ggcacgccgc gcgcgtcctt gggccgctgg ccctcggcgt
     7201 acgcgcggtc gacgacgatc gagatgtccg ccgggctctt gaggagcttc tcgaggtggc
     7261 cgcgctcgaa cacgatgtcg ccgtagagga agaggaacgg cccgctcagc tccttggagg
     7321 cgcggaagag cgaggacacc tcgttcgtcg tcgcgtactc gtcgttgtcg tagaagcgga
     7381 cgttcgggac cttgatggcc tccttcttgt acccgcgcac gacggcgacg tccttgacgc
     7441 cgcacgcgtt gagcacgtcg atctgccgct cgaggatgct cttgcccttc aggtcgagca
     7501 tcggcttcgg cagctcctcc gtgagcggca ggagcccttg gctctggccg gcggcgagga
     7561 tgacggcggt gacgcccggg ctgccggagg gcaggaagct cgactcctcc tgcttcatct
     7621 tgtcgacgcc cacgagctgg tagacgcgct cgagcggcac gaccttgtcg tcgacgctgc
     7681 cggtgtacat ctcgcgcttc agcgtctgga gcgtctccgt catcgccttg atcgacgagc
     7741 ggatcgcgtg gttcgcgaag atgatcagct tgaagccggc cttgtgcagc gtgtcgacgc
     7801 tcgtcgtgcg gtagatcgtc ggcacgcaga cgagcggcgt gttcgggcgg tcccacgcgc
     7861 gggcgaagga gagcacctcg tccgggtcct tgctcttcga gtggatgagg accatgtcgg
     7921 cgcccgcgtc cgcgtaggcg cggccgcggc ggagcgcctc ctccatcccc cagccggcga
     7981 tgagcgcctc ggtccgcgcg atgaccacga agtcgcgatc cttctgcgtc gccttcgcgg
     8041 cgcggacctt gagcgcgtgc tcctcgacgt ccgcgagctc gcgcttcacg ccggcgtaga
     8101 agctgcagcg cttcgggaag atgttgtctt ccatgcagat cgccgcgatg cccgccgcct
     8161 cgtactcctc gacgcagcgg acgacgttga cggcgttgcc gtagccgttg tcgcagtccg
     8221 cgacgaccgg gagcgacgtg ctgttcatca tcttggcggc ctggaggttc tccgccatcg
     8281 tgaggatgtt cgcgtccggc accgcgtagc tcgcggagat ctcgaagccg gaagcccaga
     8341 gcccgtcgaa ccctgcctct tcgccgatct ttgcagagag cccgttgtgc gcgccgatga
     8401 tgacgatcgg cccggggcgg gccatgagtt cgcgcagctt cctggctttg gtcacgtctc
     8461 gtccactcct ccgcgcggtg ttgccatctc cgcccgacgg gcgaccgcgg ctgcaggtgc
     8521 cgcggtgcgc gtcccaggcg agcggcgtcc cgtcgtcacc gcgcgcgggc agctccgggg
     8581 tgcgcctgat ctcgctctcc tccccgagga gccgggcctc agaacggggc ctgccttaac
     8641 accgttcgcc agtgccgcca atggcagggc acgaccgggg cagacgatcg cgagggcggc
     8701 ggagcgcgct ccgccgcgtc gggacgtgcg cgctgcggcg gtgcccgatg gcgggcgcgc
     8761 gcgatgctcg ccgcgggccc cccggccgct cagccctcgc ggccgacgac cccgcgcaag
     8821 cggaccagcc cggggcccgc gcggagcacc gcctggcacg cgagcctgag ccgcggcggg
     8881 gcgccgaggc gatcgagcag atcgcgctcg ccgcgcgcgg gcggttcgag gagctgctcc
     8941 ccttcgacga cctcgacgcg gcatgtggcg cagcgcgcgt cgcggcacga gaacacgatc
     9001 ggagcgcgcg cgtcgtcgca gacatcgatg agcctgcccg ctcccgcctc cgcggtgacg
     9061 gcggggccga gcgcgccgtc ctcgaacacg accgtgggca ccgccgatct ctcctccctg
     9121 cccggcgcgc gacgccgaga gcgcattttc tcgagcgtcg gcacgcacta tacgacgagc
     9181 gatgacggat cgctgggacg caatcatcct cggcggaggg ccgggtgggt cgacgctcgc
     9241 cgcatcgctg gcccgcctcg ggcgccgggc cctcgtgctc gagcgggaga ggttccctcg
     9301 ctttcacatc ggcgagtcgc tgctgccgct gtcccgcgag gtcttcgagc ggctcgggct
     9361 ggacgaggag ctggacgcgc gcttcctccg caaatacggc gcccggttcc tgtgctcgtc
     9421 gacggggcgg acgcggacgt acagcttcgc cgacgcgttc gagccgcggt tcgagttcgc
     9481 ctaccaggtg cagcgcgacg cgttcgacca gctgctgctc cgccacgccg cggagctcgg
     9541 ggcggaggtg cgcgagtcgt gggaggccgt cgaggtgatg ttcgagggcc cccgcgccgt
     9601 cggggtgcgc gcgcggcccc gcgctcgacc cgacggcgcc gggccggagg aggccgcggc
     9661 cgcgcgcgcc gactcgagcg acgtcgtcga gctccgggcg ccggtgatcg tcgacgcgac
     9721 ggggcgggac acgctgctcg cgtcgaggat gcggcggaag gcgcagctgg ccgagctcga
     9781 caagaccgcg ctgttcaccc actacgaggg cgtgccccgc gaggcgggga tccaccaggg
     9841 cgacatccag atcgtcctct tcgagcacgg gtggttctgg ttcatcccgt tccgcggcga
     9901 ggtgacgagc gtcggcgcgg tggtgtcgtc gagctggatc cggggccggg cgaaggggga
     9961 gcggctcgac gagctcttcg atcgcaccgt cgcgcagagc ggctgggcgc gggagttcct
    10021 cgcgagcgcg cggcgcatca ggccggtggg ggcgctcgcc gatttctcgt accggatcga
    10081 ccagctcgcc ggagacggat ggctcttcgt gggcgacgcg ggcgggttcc tcgacccgct
    10141 cttctcgacg ggcgcgcacc tcgccatcaa gggcgccgat ctggccgcca cggccatcca
    10201 ccgcgcgctc gacgccgggg acacctcgcg cgccgcgttc tcggcctacg aggcggagat
    10261 ccgctacgcc gtggatctct tcctgggggt cgttcagggt ttttacaaag gccagttccg
    10321 ggagacgctg ttcgagccga accagcggcc cacgatgcgc aagctcatca ccagcatgct
    10381 cgcgggcgac gtgttccacg ccgagcggcg gccgcagtgg gcgtcgttcc tccggcagca
    10441 gtatccggcg gaggtgcccg ccttcgcgtg aagcgcggcg ggcggccgag cgtgtgcctc
    10501 gtcgcgtggg cgctcgcccg ggcgctcggc cgtccggcgc tcaggggccg cacgcttcgc
    10561 ggtccaggac cgcgtcgctc atctgcttgc aggcggccgc gagcgcgacg cgggcctccg
    10621 ccctcgcgtc gcccttcagc gcctcgtcgt cggcctccgc cctggcctcg agcacgtcgc
    10681 gcgcgatccg gatcgcggcc tcgtggctct tcctgctctc cgcgggcagc ttgctggcgc
    10741 aggtggtcat cgtggccagg tagctgtcgc aggcgtcgac ccccgtgctg tcgaggtcgg
    10801 ccttccccgg atcgccgcct gctttgccgc agccgagggc gaaggtgccc cagagaagaa
    10861 gtgccaggtg agctctcgcc atcgtcgcgc gcgccggagc gccgcgcgcc gctggaggcc
    10921 ggagctggcc acctcgcgcg ctgcccggcg cccgcgcacc ctgccatgag cccgcgccgc
    10981 ggggcaattt tcggtggctc aggcgcggcg gcgcgccctg ccctgcgcct gcgccgcggg
    11041 gagagcctgg cgggtcaggc gcggatcagc aggatggcgt gctcgtggcg cgggcggcgc
    11101 tggaaggcgc gcgccgtggg gcggtggaag tgggggcgcg gctgcgacgc gaccgcgcgg
    11161 accgcgaagc gcgcgccgga cgcggcggcc ctgaccacgt cgaccgcgta gaccggcgcg
    11221 ccggcgacca cgctgtcggc gatcagcagc acgagcggcg cgccgctccg gaggacgcgc
    11281 gcgagcgcgg tgagcacgcc gccgagctcg tcgcgccagc gcgcgcggcc cgcctcgggg
    11341 ccgagcgggt cgaggtgccg gcgggccccg atctcgtcct gctcgaagcg ggcgctgcgg
    11401 agccggagcc agcgcagcct cgcctcgtgg tgggcgaggt agtcgtacac gcccgggtag
    11461 ggcggcgacg tgatcgcgag gtggacggag ccggcctcga cgccgcggag cacgcgcgcg
    11521 tctccctcct cgacgagcgc gggcgggctc gctgcgagcg gcacggcgac ctcggcgagg
    11581 cgctgggcga gctcctccgc cttgcggatg aagagccgcg ccggatagcc ggcggcgatc
    11641 cgccgcggca gctcgtgctc cgacgtgtcg gacgtgcggc ggctgagctt cgtcaggatg
    11701 gcggagagga cgagctcgag atcggcgcgg agcgcgtcgg cgccgtggcc cgcgaggcgg
    11761 tcgaggccga cgcggagccc gtcgagctcg aggagcacgt gcggctcgaa cagggcgacg
    11821 tcctcggggc cgtaccggcg gctcggaccg gcgcgcgcct tgcggcgctc atcggccgcg
    11881 gccgcgacct cgcgggcggc ggcgacgagc cgctcgcgct cgccgggggt gctgccctgc
    11941 accttgaggc gggcgaggcg cacggccagc gggttcgcgt cgacgccgat cgccgcccgg
    12001 cccgagagcc gggcctcgac gaggacggtg ccgctgccgc agaaggggtc gagcacccgc
    12061 tcgcccggcc tcgagaggcc ctcgatcagc cggcgggcgg tgtccgggtg catccgggcc
    12121 gggtagctgt ggaacccgtg cacgtgcgcg cgcgccgctt cctccgccgt gctcgagctg
    12181 gccacgtcga gcgcgtgggc gagcttcgcg gcgctctcgg ggtcgccctc gagcaccgtc
    12241 gcgccgccga tgtgggtcag ggcgcggcgc tcctgggacg cgggccggcc cgcgtgggcc
    12301 ttctgctgcg ggcctggctt cggcttggga tcagcgcttc gcggggtcga catgggcggt
    12361 ccgttgcgtc aggggctcgg cggcgaaggc ttcctcttcg gcggcgaggg cgtgcgccac
    12421 gctctcggcc ccggcctcgc cccggtcttc gtcgcgcgcc gcgccgacgc gcagcttcgg
    12481 cgcatagccg aactcgcccg cggggccgat cgcgccgcgc acgacgtcgt tgacctccag
    12541 cagggcgagg agctcctcgg cctgggactc ggcgatgcgg agggtcgagg cgagcccgcc
    12601 ggcggtgagc gggccctcgg cctggcgggc gacgtcggag gcgacggaga cccaggcggc
    12661 gtcgagcgcg ggcgcgatgt cccggctccg cgacttcgcc cgccggagag cccagagggc
    12721 gaaggcgccg acgggcgcca tggtgaggag cccggcggtg aagagcccga cgctcgcgcc
    12781 gaggacgagc agcagcacgg cgaacaggaa cagctcgaag ccgagcagcg cgctggccgc
    12841 gacgcccgcg gcgcgccaga ccgagcgcgc cgaggccgcc gcgcgcgcct tctggagcag
    12901 cggcacctcg cggccggatc gctcgacgcg ggcgtcggcg acggggacgc gcgggcctcc
    12961 gcaggcgtcg cacgcgaagc gcagctcgag gtgcgccgag gcgccggtca cgccgccgca
    13021 gtgcgggcag gcctcggcgc gcgcggccgc gccgcactgc gggcagcgat cgccctccgg
    13081 cgcgagcgcc gcgtcgcaca cgcggcagcg ggcggcgccg ggcgacgcgt cgctcacggc
    13141 gcgctcgcgg atggggccga gcgggcgccg cccacgctgc gcagcacggc gtcgaacagg
    13201 gcgcgcccgt ccgcgcggta gtggccctgg aagggctcgc tcatccgttc ggggtgcggc
    13261 atcagcccga gcacgttccg ccggggcccg ccgtagatgc cggcgatgtc catcgccgat
    13321 ccgttggggt tcgcgtcgcc gccgaccagc ccctcccggt cgcagtactg cagcgcgatg
    13381 cggacctgga gcacgtcgcg gagcgtatgg atcatttcgg cgtcggcgct cgagcccggg
    13441 aagatgacca cggtc
//
